Evaluation of a New Topical Treatment for Acne with Azelaic Acid-Loaded Nanoparticles

Efficacy of topical azelaic acid gel in the treatment of mild-moderate acne vulgaris.

BACKGROUND Twenty percent azelaic acid gel is recommended as a topical treatment for acne due to its favorable profile. AIM Our objective in this study was to evaluate the efficacy of 20% azelaic acid gel in the treatment of mild to moderate acne vulgaris. METHODS This was a double blind, randomized clinical trial. Sixty patients with mild to moderate acne vulgaris were selected randomly to...

New Topical Acne Treatment

Photographic Evaluation of 15% Azelaic Acid Gel in Acne Rosacea

Objective: Acne rosacea is a difficult to treat disease and current treatments remain unsatisfactory. Our aim was to assess and present the photographic evaluation of the effectiveness and tolerability of azelaic acid 15 % gel for the treatment of acne rosacea. Methods: Healthy male and female adult outpatients (>18 years of age) with mild to moderate acne rosacea. All patients were instructed ...

Lomustine Loaded Superparamagnetic Iron Oxide Nanoparticles Conjugated with Folic Acid for Treatment of Glioblastoma Multiforma (GBM)

This study aimed to improve delivery of lomustine as a chemotherapeutic agent and to increase its uptake by U87-MG cancer cells via synthesizes LN-FA-PG-SPIONs (lomustine loaded polyglycerol coated superparamagnetic iron oxide nanoparticles conjugated with folic acid). Nanoparticles were synthesized by thermal decomposition method and characterized using TEM (transmission microscope), FTIR (Fou...

Lomustine Loaded Superparamagnetic Iron Oxide Nanoparticles Conjugated with Folic Acid for Treatment of Glioblastoma Multiforma (GBM)

This study aimed to improve delivery of lomustine as a chemotherapeutic agent and to increase its uptake by U87-MG cancer cells via synthesizes LN-FA-PG-SPIONs (lomustine loaded polyglycerol coated superparamagnetic iron oxide nanoparticles conjugated with folic acid). Nanoparticles were synthesized by thermal decomposition method and characterized using TEM (transmission microscope), FTIR (Fou...